Acute esophageal necrosis

Last revised by Liz Silverstone on 10 Jun 2024

Acute esophageal necrosis, sometimes known as black esophagus or esophageal stroke is a rare entity characterized by patchy or diffuse circumferential black pigmentation of the esophageal mucosa from ischemic necrosis.

On endoscopy there is distal diffuse circumferential blackening of the esophageal mucosa that stops abruptly at the gastro-esophageal junction.

It is rare with <150 cases reported in the literature up until 2024 1. There is a greater male predilection 5.

It can have a multifactorial etiology.

The distal third of the esophagus is thought to be most commonly affected (97% of cases) due to poor vascularity. 

It generally carries a poor prognosis 3,5 and presents with life-threatening upper gastrointestinal hemorrhage. Most cases are conservatively managed 3. It may lead to esophageal perforation.

It is thought to have been been first reported in 1990 and was then classified as a separate syndrome in 2007.

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