Adams-Oliver syndrome
Citation, DOI, disclosures and article data
Citation:
Weerakkody Y, Knipe H, Bell D, et al. Adams-Oliver syndrome. Reference article, Radiopaedia.org (Accessed on 27 Mar 2025) https://doi.org/10.53347/rID-15845
rID:
15845
Article created:
Disclosures:
At the time the article was created Yuranga Weerakkody had no recorded disclosures.
View Yuranga Weerakkody's current disclosures
Last revised:
Disclosures:
At the time the article was last revised Henry Knipe had the following disclosures:
- Integral Diagnostics, Shareholder (ongoing)
- Micro-X Ltd, Shareholder (ongoing)
These were assessed during peer review and were determined to not be relevant to the changes that were made.
View Henry Knipe's current disclosures
Revisions:
9 times, by
9 contributors -
see full revision history and disclosures
Systems:
Sections:
Synonyms:
- Adams-Oliver syndrome (AOS)
- Aplasia cutis congenita with terminal transverse limb defects
- Congenital scalp defects with distal limb reduction anomalies
- Absence defect of limbs, scalp and skull
Adams-Oliver syndrome is a rare disorder characterised by aplasia cutis congenita (missing hair and/or skin) and variable degrees of terminal transverse limb defects. It may be accompanied by orofacial and cardiac malformations 6.
Pathology
Associations
polymicrogyria: may be associated with a variant of Adams-Oliver syndrome 3
References
- 1. Temtamy S, Aglan M, Ashour A, Zaki M. Adams-Oliver Syndrome: Further Evidence of an Autosomal Recessive Variant. Clin Dysmorphol. 2007;16(3):141-9. doi:10.1097/MCD.0b013e3280f9df22 - Pubmed
- 2. Rypens F, Dubois J, Garel L, Fournet J, Michaud J, Grignon A. Obstetric US: Watch the Fetal Hands. Radiographics. 2006;26(3):811-29; discussion 830-1. doi:10.1148/rg.263055113 - Pubmed
- 3. Amor D, Leventer R, Hayllar S, Bankier A. Polymicrogyria Associated with Scalp and Limb Defects: Variant of Adams-Oliver Syndrome. Am J Med Genet. 2000;93(4):328-34. doi:10.1002/1096-8628(20000814)93:4<328::aid-ajmg13>3.0.co;2-0 - Pubmed
- 4. Koiffmann C, Wajntal A, Huyke B, Castro R. Congenital Scalp Skull Defects with Distal Limb Anomalies (Adams-Oliver Syndrome--McKusick 10030): Further Suggestion of Autosomal Recessive Inheritance. Am J Med Genet. 1988;29(2):263-8. doi:10.1002/ajmg.1320290203 - Pubmed
- 5. Küster W, Lenz W, Kääriäinen H, Majewski F. Congenital Scalp Defects with Distal Limb Anomalies (Adams-Oliver Syndrome): Report of Ten Cases and Review of the Literature. Am J Med Genet. 1988;31(1):99-115. doi:10.1002/ajmg.1320310112 - Pubmed
- 6. Suarez E, Bertoli M, Eloy J, Shah S. Case Report and Review of Literature of a Rare Congenital Disorder: Adams-Oliver Syndrome. BMC Anesthesiol. 2021;21(1):117. doi:10.1186/s12871-021-01339-0 - Pubmed
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