Adenocarcinoma of the cervix

Adenocarcinoma of the cervix is a histological subtype of carcinoma of the cervix

Cervical adenocarcinoma is less common than squamous cell carcinomas (SCC) of the cervix, accounting for ~12.5% of all cervical cancer. Their proportionate prevalence is thought to be increasing and this is thought to be due to being less readily detected by exfoliative cytology obtained with the Papanicolaou test 2-3.

As with squamous cell carcinomas, adenocarcinoma type also generally tend to arise from the squamocolumnar junction (SCJ). They may arise from a precursor lesion, cervical adenocarcinoma in situ, and are almost always associated with HPV 18 5

Aside from smoking, cervical adenocarcinoma has the same risk factors as cervical SCC (see: cervical carcinoma for further details of risk factors) 6.

There are several subtypes that fall under this category and include:

Adenocarcinomas in general (compared with squamous cell counterparts) are thought to generally give higher rates of thoracic and adrenal metastatic disease 1.

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Article information

rID: 17841
System: Gynaecology
Tag: cases
Synonyms or Alternate Spellings:
  • Cervical adenocarcinoma
  • Adenocarcinoma of cervix
  • Adenocarcinoma of uterine cervix
  • Adenocarcinoma (cervix)

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