Adenoid cystic carcinoma of lacrimal gland

Last revised by Yuranga Weerakkody on 29 Aug 2023

Adenoid cystic carcinoma (ACC) of the lacrimal glands is an extraconal malignancy usually originating from the orbital lobe of the lacrimal gland.

It often presents with orbital pain and paresthesia, since this type of tumor is frequently associated with perineural spreading. The tumor is highly aggressive and has a poor prognosis and high recurrence rate 3.

CT may show an infiltrative mass involving the lacrimal gland, very often associated with bony destruction, showing enhancement after contrast administration.

Signal characteristics include:

  • T1: homogeneously hypointense

  • T2: usually isointense, but sometimes hypointense (basaloid subtype)

  • T1 C+ (Gd): moderate enhancement

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