Adenoid cystic carcinoma of the salivary glands is the second most common malignancy involving the minor salivary glands behind mucoepidermoid carcinoma and the second most common malignancy involving the parotid gland.
Adenoid cystic carcinomas arise more commonly in the minor salivary glands (~55%) than in the major salivary glands. They are the most common sinonasal tumors of salivary origin. They are locally aggressive with a propensity for perineural spread 5.
Generally, a distinction is made radiologically between low-grade and high-grade adenoid cystic carcinomas. Low-grade tumors tend to be well-defined, in contradistinction to high-grade tumors, which appear infiltrative. However, both subtypes are usually homogeneously enhancing after contrast administration.
- T1: hypo- to isointense
- T2: slightly hyperintense, with higher grades being markedly hyperintense
- T1 C+ (Gd): homogeneous enhancement
- 1. Dubergé T, Bénézery K, Resbeut M et-al. [Adenoid cystic carcinoma of the head and neck: a retrospective series of 169 cases]. Cancer Radiother. 16 (4): 247-56. doi:10.1016/j.canrad.2012.02.003 - Pubmed citation
- 2. Du LX, Yuan JP, Guan H et-al. [Magnetic resonance imaging for diagnosis of parotid malignant tumors and the pathological basis]. Nan Fang Yi Ke Da Xue Xue Bao. 2010;30 (5): 1107-10. Nan Fang Yi Ke Da Xue Xue Bao (link) - Pubmed citation
- 3. Godge P, Sharma S, Yadav M. Adenoid cystic carcinoma of the parotid gland. Contemp Clin Dent. 2012;3 (2): 223-6. doi:10.4103/0976-237X.96838 - Free text at pubmed - Pubmed citation
- 4. Christe A, Waldherr C, Hallett R et-al. MR imaging of parotid tumors: typical lesion characteristics in MR imaging improve discrimination between benign and malignant disease. AJNR Am J Neuroradiol. 2011;32 (7): 1202-7. doi:10.3174/ajnr.A2520 - Pubmed citation
- 5. Yih WY, Kratochvil FJ, Stewart JC. Intraoral minor salivary gland neoplasms: review of 213 cases. (2005) Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons. 63 (6): 805-10. doi:10.1016/j.joms.2005.02.021 - Pubmed