Adenosquamous carcinoma of lung
Adenosquamous carcinoma of the lung is a rare type of non-small cell lung cancer containing both components of lung adenocarcinoma and lung squamous cell carcinoma (SCC).
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Epidemiology
It is thought to constituting 0.4-4% of cases non-small cell lung cancer.
Risk factors
- cigarette smoking 8
Pathology
The definition of adenosquamous carcinoma indicates a carcinoma showing components of adenocarcinoma and squamous cell carcinoma, with each comprising at least 10% of the tumor 4.
Location
There may be a slight predominance towards the periphery of the lung 5-6.
Radiographic features
General
There appears to be a wide imaging spectrum both in terms of size and morphology 5. Differentiation from other histological forms on imaging grounds alone can be difficult, if not impossible. They usually present as a single lesion, with mean tumor size ranging from 2.8 to 3.8 cm (range 0.6-11 cm), based on two studies 5-6.
Treatment and prognosis
It is thought to be more aggressive than both pure adenocarcinomas of the lung and pure squamous cell carcinomas of the lung 1. The early-stage disease may be amenable to surgery. There may also be an increased rate of lymph node metastases at the time of presentation compared with other histological types 7.
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Chest
- imaging techniques
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chest x-ray
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approach
- adult
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airspace opacification
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- lobar consolidation
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atelectasis
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- cardiomediastinal contour
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- fissures
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- nipple shadow
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lines and stripes
- anterior junction line
- posterior junction line
- right paratracheal stripe
- left paratracheal stripe
- posterior tracheal stripe/tracheo-esophageal stripe
- posterior wall of bronchus intermedius
- right paraspinal line
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- azygo-esophageal recess
- spaces
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- air bronchogram
- big rib sign
- Chang sign
- Chen sign
- coin lesion
- continuous diaphragm sign
- dense hilum sign
- double contour sign
- egg-on-a-string sign
- extrapleural sign
- finger in glove sign
- flat waist sign
- Fleischner sign
- ginkgo leaf sign
- Golden S sign
- Hampton hump
- haystack sign
- hilum convergence sign
- hilum overlay sign
- Hoffman-Rigler sign
- holly leaf sign
- incomplete border sign
- juxtaphrenic peak sign
- Kirklin sign
- medial stripe sign
- melting ice cube sign
- more black sign
- Naclerio V sign
- Palla sign
- pericardial fat tag sign
- Shmoo sign
- silhouette sign
- snowman sign
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approach
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chest x-ray
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bronchiectasis
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tracheal stenosis
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bronchial stenosis
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tracheal stenosis
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interstitial lung disease (ILD)
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hypersensitivity pneumonitis
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- etiology
- bird fancier's lung: pigeon fancier's lung
- farmer's lung
- cheese workers' lung
- bagassosis
- mushroom worker’s lung
- malt worker’s lung
- maple bark disease
- hot tub lung
- wine maker’s lung
- woodsman’s disease
- thatched roof lung
- tobacco grower’s lung
- potato riddler’s lung
- summer-type pneumonitis
- dry rot lung
- machine operator’s lung
- humidifier lung
- shower curtain disease
- furrier’s lung
- miller’s lung
- lycoperdonosis
- saxophone lung
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idiopathic interstitial pneumonia (mnemonic)
- acute interstitial pneumonia (AIP)
- cryptogenic organizing pneumonia (COP)
- desquamative interstitial pneumonia (DIP)
- non-specific interstitial pneumonia (NSIP)
- idiopathic pleuroparenchymal fibroelastosis
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pneumoconioses
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lung cancer
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non-small-cell lung cancer
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adenocarcinoma
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adenocarcinoma
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lung cancer invasion patterns
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non-small-cell lung cancer