Adenosquamous carcinoma of lung

Adenosquamous carcinoma (ASC) of the lung is a rare type of non-small cell lung cancer.

It is thought to constituting 0.4-4% of cases non-small cell lung cancer.

The definition of adenosquamous carcinoma indicates a carcinoma showing components of adenocarcinoma and squamous cell carcinoma, with each comprising at least 10% of the tumor 4.

There may be a slight predominance towards the periphery of the lung 5-6.

There appears to be a wide imaging spectrum both in terms of size and morphology 5. Differentiation from other histological forms on imaging grounds alone can be difficult. They usually present as a single lesion, with mean tumor size ranging from 2.8 to 3.8 cm (range 0.6-11 cm), based on two studies 5-6.

It is thought to be more aggressive than both pure adenocarcinoma of the lung and pure squamous cell carcinoma of the lung 1. Early stage disease may be amenable to surgery. There may also be an increased rate of lymph node metastases at the time of presentation compared with other histological types 7

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Article information

rID: 22954
System: Chest, Oncology
Tag: cases
Synonyms or Alternate Spellings:
  • Adenosquamous lung carcinoma
  • Adenosquamous carcinoma of the lung
  • Adenosquamous carcinoma of lungs
  • Adenosquamous carcinoma of the lungs
  • Adenosquamous carcinoma (ASC) of the lung
  • Adenosquamous carcinoma (ASC) of the lungs
  • ASC lung
  • Adenosquamous lung carcinomas

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Cases and figures

  • Case 1: with widespread intrapulmonary metastases
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