Adie syndrome, also known as Holmes-Adie syndrome, is a rare neurological disorder.
Adie syndrome is a rare condition which is most commonly seen in young females in their fourth decade of life 2,3.
Patients most commonly present with a classic triad of:
- absent deep tendon reflexes, e.g. ankle jerk
- an Adie pupil: tonically dilated and responds poorly or not at all to light
Unilateral pupillary symptoms are more common than bilateral 2,3.
History and etymology
It was named after the British-Australian neurologist William John Adie (1886 - 1935) 1.
- 1. Pearce JM. William John Adie (1886-1935). (2004) Journal of neurology, neurosurgery, and psychiatry. 75 (8): 1111. doi:10.1136/jnnp.2003.020321 - Pubmed
- 2. Sherrill TM, Lutz DJ. Adie syndrome: a case report. (1997) J Am Board Fam Pract. 1;10(6):439-40.
- 3. Sarao MS, Sharma S. Adie Syndrome. (2018) Pubmed