Adie syndrome

Adie syndrome, also known as Holmes-Adie syndrome, is a rare neurological disorder.

Adie syndrome is a rare condition which is most commonly seen in young females in their fourth decade of life 2,3.

Patients most commonly present with a classic triad of:

  1. diaphoresis
  2. absent deep tendon reflexes, e.g. ankle jerk
  3. an Adie pupil: tonically dilated and responds poorly or not at all to light

Unilateral pupillary symptoms are more common than bilateral 2,3

It is thought to result form damage to the ciliary ganglion and the dorsal root ganglion by viral or bacterial infections, however there are idiopathic etiologies 1,3.

It was named after the British-Australian neurologist William John Adie (1886 - 1935) 1

Article information

rID: 5507
Section: Syndromes
Synonyms or Alternate Spellings:
  • Holmes-Adie syndrome

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