Adrenal hyperplasia

Adrenal hyperplasia refers to nonmalignant growth (enlargement) of the adrenal glands and is a rare cause of ACTH-independent Cushing syndrome, with unilateral adrenal cortical adenomas being the commonest. 20% of Conn syndrome cases are secondary to adrenal hyperplasia. In diffuse hyperplasia, the limbs of the adrenal glands are >5 cm in length and >10 mm in thickness. 

Classification

Adrenal hyperplasia can be classified according to:

  • enlarged limbs of one or both adrenal glands >10 mm thick
  • normal adrenal morphology maintained
  • nodular or uniform
MRI
  • high lipid content and thus may demonstrate signal dropout in out-of-phase chemical shift imaging
  • signal dropout due to lipid content overlaps with adrenal cortical adenomas
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Article information

rID: 17118
System: Urogenital
Synonyms or Alternate Spellings:
  • Adrenal cortical hyperplasia
  • Adrenal hyperplasia : general

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Cases and figures

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    Case 1: due to thymic carcinoid tumour
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