Adrenal hyperplasia

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Adrenal hyperplasia refers to nonmalignant growth (enlargement) of the adrenal glands and is a rare cause of 70% of the cases ofACTH independent Cushing syndrome and with unilateral adrenal cortical adenomas being the commonest. 20% of the of Conn's syndrome cases of Conn syndromeare secondary to adrenal hyperplasia. In In diffuse hyperplasia, the limbs of the adrenal glands are >5 cm in length and >10mm in thickness. 

Pathology

Classification

Adrenal hyperplasia can be classified according to:

Radiographic features

General
  • Enlarged limbs of one or both adrenal glands >10mm
  • Normal adrenal morphology maintained
  • Nodular or Uniform
MRI
  • High lipid content and thus may demonstrate signal drop out in out-of-phase imaging
  • Signal drop out due to lipid content overlaps with adrenal cortical adenomas

See also

  • -<p><strong>Adrenal hyperplasia</strong> refers to nonmalignant growth (enlargement) of the <a href="/articles/adrenal-gland">adrenal glands</a> and is a cause of 70% of the cases of <a href="/articles/cushing-syndrome">Cushing syndrome</a> and 20% of the cases of <a href="/articles/conn-syndrome">Conn syndrome</a>. In diffuse hyperplasia, the limbs of the adrenal glands are &gt;5 cm in length and &gt;10mm in thickness. </p><h4>Pathology</h4><h5>Classification</h5><p>Adrenal hyperplasia can be classified according to:</p><ul>
  • +<p><strong>Adrenal hyperplasia</strong> refers to nonmalignant growth (enlargement) of the <a href="/articles/adrenal-gland">adrenal glands</a> and is a rare cause of ACTH independent <a href="/articles/cushing-syndrome">Cushing syndrome</a> with unilateral adrenal cortical adenomas being the commonest. 20% of Conn's syndrome cases are secondary to adrenal hyperplasia.  In diffuse hyperplasia, the limbs of the adrenal glands are &gt;5 cm in length and &gt;10mm in thickness. </p><h4>Pathology</h4><h5>Classification</h5><p>Adrenal hyperplasia can be classified according to:</p><ul>
  • -</ul><h4>See also</h4><ul><li><a href="/articles/bilateral-adrenal-enlargement">bilateral adrenal enlargement</a></li></ul>
  • +</ul><h4>Radiographic features</h4><p> </p><h5>General</h5><ul>
  • +<li>Enlarged limbs of one or both adrenal glands &gt;10mm</li>
  • +<li>Normal adrenal morphology maintained</li>
  • +<li>Nodular or Uniform</li>
  • +</ul><p> </p><h5>MRI</h5><ul>
  • +<li>High lipid content and thus may demonstrate signal drop out in out-of-phase imaging</li>
  • +<li>Signal drop out due to lipid content overlaps with adrenal cortical adenomas</li>
  • +</ul><p> </p><h4>See also</h4><ul><li><a href="/articles/bilateral-adrenal-enlargement">bilateral adrenal enlargement</a></li></ul>

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