Adrenal lymphangiomas, also known as cystic adrenal lymphangiomas, are rare, benign vascular adrenal lesions.
According to one series, there may be a slight right-sided and female predilection 3.
They usually remain asymptomatic throughout life and are almost always incidentally detected. Rarely patients may have abdominal pain 3.
It is supposed to occur as a result of a developmental abnormality of lymphatic channels 4.
- D2-40 cytoplasmic staining tends to be positive 6
- AE1/AE3 staining tends to be negative 6
Typically seen as a cystic adrenal lesion. Internal septations may be present.
They tend to present as relatively large lesions with an average size ranging around 3 cm 6.
Treatment and prognosis
They are benign lesions although adrenalectomy is considered as part of treatment.
- 1. Ates LE, Kapran Y, Erbil Y et-al. Cystic lymphangioma of the right adrenal gland. Pathol. Oncol. Res. 2006;11 (4): 242-4. Pubmed citation
- 2. Longo JM, Jafri SZ, Bis KB. Adrenal lymphangioma: a case report. Clin Imaging. 2001;24 (2): 104-6. Pubmed citation
- 3. Ellis CL, Banerjee P, Carney E et-al. Adrenal lymphangioma: clinicopathologic and immunohistochemical characteristics of a rare lesion. Hum. Pathol. 2011;42 (7): 1013-8. doi:10.1016/j.humpath.2010.10.023 - Pubmed citation
- 4. Secil M, Demir O, Yorukoglu K. MRI of adrenal lymphangioma: a case report. Quant Imaging Med Surg. 2014;3 (6): 347-8. doi:10.3978/j.issn.2223-4292.2013.12.07 - Free text at pubmed - Pubmed citation
- 5. Bettaïeb I, Mekni A, Bédioui H et-al. Huge cystic lymphangioma of the adrenal gland. A case report and review of the literature. Pathologica. 2007;99 (1): 19-21. Pubmed citation
- 6. Zhao M, Gu Q, Li C et-al. Cystic lymphangioma of adrenal gland: a clinicopathological study of 3 cases and review of literature. Int J Clin Exp Pathol.7 (8): 5051-6. Free text at pubmed - Pubmed citation