AIDS embryopathy
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Acquired immuno deficiencyimmunodeficiency syndrome (AIDS) embryopathy is characterised by a group of dysmorphic features, which manifests either before or after birth in offsprings of women who are infected by HIV virus. The diagnosis, however, is in disfavour according to some authors 2.
Pathology
Transplacental infection occurs generally in early gestation. The rate of maternal to fetal viral transmission varies from varies from 14% in Europe to 45% in Africa. Of all children infected with HIV virus, approximately 99% wherewere infected from their mothers.
Radiographic features
Antenatal ultrasound
Sonographic features are are broad and include:
- signs of fetal infection may be present
- evidence of fetal demise
- intrauterine growth retardation
- microcephaly
- craniofacial abnormalities, present in 50-75% of cases, can give characteristic facial appearances and include:
- prominent, square or box
like-like forehead - lateral bossing
- hypertelorism
- flat nasal bridge and short nose
- prominent, square or box
-<p><strong>Acquired immuno deficiency syndrome (AIDS) embryopathy</strong> is characterised by a group of dysmorphic features, which manifests either before or after birth in offsprings of women who are infected by HIV virus. The diagnosis however is in disfavour according to some authors <sup>2</sup>.</p><h4>Pathology</h4><p>Transplacental infection occurs generally in early gestation. The rate of maternal to fetal viral transmission varies from 14% in Europe to 45% in Africa. Of all children infected with HIV virus, approximately 99% where infected from their mothers.</p><h4>Radiographic features</h4><h5>Antenatal ultrasound</h5><p>Sonographic features are broad and include:</p><ul>- +<p><strong>Acquired immunodeficiency syndrome (AIDS) embryopathy</strong> is characterised by a group of dysmorphic features, which manifests either before or after birth in offsprings of women who are infected by HIV virus. The diagnosis, however, is in disfavour according to some authors <sup>2</sup>.</p><h4>Pathology</h4><p>Transplacental infection occurs generally in early gestation. The rate of maternal to fetal viral transmission varies from 14% in Europe to 45% in Africa. Of all children infected with HIV virus, approximately 99% were infected from their mothers.</p><h4>Radiographic features</h4><h5>Antenatal ultrasound</h5><p>Sonographic features are broad and include:</p><ul>
-<li>evidence of <a href="/articles/fetal-death-2">fetal demise</a>- +<li>evidence of <a href="/articles/fetal-death-in-utero-1">fetal demise</a>
-<li><a href="/articles/intra-uterine-growth-restriction-2">intrauterine growth retardation</a></li>- +<li><a href="/articles/intrauterine-growth-restriction">intrauterine growth retardation</a></li>
-<li>prominent, square or box like forehead</li>- +<li>prominent, square or box-like forehead</li>
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