Air-space opacification (summary)

Changed by Jeremy Jones, 24 May 2018

Updates to Article Attributes

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This is a basic article for medical students and other non-radiologists

Air-space opacification is a descriptive term that refers to filling of the lung parenchyma with material that attenuates x-rays more than the unaffected surrounding lung tissue. It is the radiological correlate of the pathological diagnosis of pulmonary consolidation.

Reference article

This is a summary article; read more in our article on air-space opacification.

Summary

  • anatomy
  • pathophysiology
    • material fills the lung parenchyma
      • fluid: pulmonary oedema 
      • pus: pneumonia
      • blood: pulmonary haemorrhage
      • cells: cancer
      • protein: alveolar proteinosis (rare)
    • appearancedistribution
      • patchy
        • air-space filling is incomplete and non-contiguous
        • residual gas within the alveoli
      • lobar
        • complete filling of a lobe of the lung
        • clear delineation between consolidation and adjacent gas-filled structures
          • the remainder of the lung or in bronchi travelling through the lobe
        • no margin between consolidation and other soft-tissue density structures
          • mediastinum or diaphragm
    • distribution
      • multifocal
        • symmetrical or asymmetrical
        • perihilar or peripheral
        • often non-specific without clinical history and examination findings
  • common pathology

Imaging

  • role of imaging
    • confirm air-space opacification  or pleural effusion where possible
    • help to determine the cause, e.g. other signs of heart failure
    • identify complications, e.g. abscess formation
    • demonstrate accompanying pathology, e.g. effusion or empyema
    • determine severity and extent, e.g. number of lobes involved, uni- or bilaterality
  • radiographic featurescommon pathology

Radiographic features

Chest x-ray
  • normal air-filled lung is black
  • air-space opacification is radiopaque (white)
  • aerated bronchi
  • CT chest
    • air-space opacification looks very similar to the chest x-ray
      • distribution can be assessed more accurately
      • assessment of complications is more accurate
    • -<li>appearance<ul>
    • +<li>distribution<ul>
    • -</ul>
    • -</li>
    • -<li>distribution<ul><li>multifocal<ul>
    • +<li>multifocal<ul>
    • -</li></ul>
    • -<li>
    • -<strong>common pathology</strong><ul>
    • -<li><a href="/articles/pneumonia-summary">pneumonia</a></li>
    • -<li><a href="/articles/pulmonary-oedema-summary">pulmonary oedema</a></li>
    • -<li><a href="/articles/lung-cancer-summary">lung cancer</a></li>
    • -</ul><h4>Imaging</h4><ul>
    • -<li>confirm air-space opacification<ul><li>differentiate from <a href="/articles/atelectasis">atelectasis</a>
    • -</li></ul>
    • -</li>
    • +<li>confirm air-space opacification and differentiate from <a href="/articles/atelectasis">atelectasis</a> or <a title="Pleural effusion (summary)" href="/articles/pleural-effusion-summary">pleural effusion</a> where possible</li>
    • -<strong>radiographic features</strong><ul>
    • -<li>
    • -<a href="/articles/chest-x-ray-summary">chest x-ray</a><ul>
    • +<strong>common pathology</strong><ul>
    • +<li><a href="/articles/pneumonia-summary">pneumonia</a></li>
    • +<li><a href="/articles/pulmonary-oedema-summary">pulmonary oedema</a></li>
    • +<li><a href="/articles/lung-cancer-summary">lung cancer</a></li>
    • +</ul>
    • +</li>
    • +</ul><h4>Radiographic features</h4><h5>Chest x-ray</h5><ul>
    • -</ul>
    • -</li>
    • -<li>
    • -<a href="/articles/ct-chest-summary">CT chest</a><ul><li>air-space opacification looks very similar to the chest x-ray<ul>
    • +</ul><h5>CT chest</h5><ul><li>air-space opacification looks very similar to the chest x-ray<ul>
    • -</li></ul>
    • -</li>
    • -</ul>
    • -</li>
    • -</ul>
    • +</li></ul>

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