Airway centered interstitial fibrosis

Dr Henry Knipe and Dr Yuranga Weerakkody et al.

Airway centered interstitial fibrosis is a rare subtype of pulmonary fibrosis with variable outcomes.


It is characterized by fibrosis of the respiratory bronchioles and the peribronchiolar interstitium. It may be triggered by exogenous agents or endogenous autoimmune conditions such as rheumatoid arthritis.

Some of the exogenously triggered precipitants include:

Treatment and prognosis

It is thought to have better survival when compared with idiopathic pulmonary fibrosis.

Article information

rID: 72880
System: Chest
Tag: cases
Synonyms or Alternate Spellings:
  • Airway centred interstitial fibrosis (ACIF)

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