Amniocentesis

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Amniocentesis, also known as amniotic fluid testing or AFT, is a diagnostic or therapeutic medical procedure primarily used in prenatal diagnosis of chromosomal abnormalities and fetal infections.

A small amount of amniotic fluid (15-20 ml), which contains fetal tissue, is extracted from the amniotic sac surrounding a developing fetus, and the fetal DNA is examined for genetic abnormalities. It is usually performed under ultrasound guidance and is performed between the 15th-20th week of pregnancy. If performed after 20 weeks it is often termed a late amniocentesis.

Indications
  • prenatal genetic studies
  • assessment of fetal lung maturity
  • TORCH infection or chorioamnionitis
  • haemoglobinopathies and degree of hemolytic anaemia
  • blood or platelet type
  • neural tube defects
  • therapeutic amniocentesis: to remove excess amniotic fluid in symptomatic polyhydramnios or twin-to-twin transfusion syndrome
Potential risks

See also

Ultrasound - obstetric
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Article information

rID: 14699
System: Obstetrics
Tag: cases
Synonyms or Alternate Spellings:
  • Amniotic fluid testing
  • AFT
  • Amniotic fluid testing (AFT)

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