Amoebic colitis

Amoebic colitis is a type of infectious colitis, more common in tropical and subtropical areas. The causative agent is a trophozoite of Entamoeba histolytica. The cyst form may live normally in the colon as commensal.

Amoebic colitis presents with abdominal pain and dysentery.

  • appearances of infectious colitis on CT are variable and nonspecific
  • amoebic colitis may present with ulceration and skip lesions mimics Crohn's disease
  • collar button or aphthus ulcers 
  • ameboma: large lesions mimic cancer 
  • any part of the colon may be involved, but typically the cecum and rectum are more severely affected
  • ileum is spared; helps to differentiate it from Crohn's or TB which typically involves the terminal ilium 

Antiparasitic therapy for amoebic colitis requires confirmation with laboratory investigation, including fecal exam.

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Article Information

rID: 32065
Section: Pathology
Synonyms or Alternate Spellings:

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