Amyoplasia congenita

Dr Jeremy Jones and Radswiki et al.

Amyoplasia congenita is a syndrome characterized by multiple specific congenital joint contractures, associated with substitution of muscular tissue by fibrosis and adipose tissue.


The estimated incidence is at  1: 10000 live births. There may be a higher prevalence with twin pregnancies 1.


The muscles are hypoplastic and replaced by a mixture of fat and fibrosis


It is throught to occur sporadically

Radiographic features

Antenatal ultrasound

Features include


The term a-myo-plasia essentially derives from the Latin meaning no-muscle-development

Article information

rID: 15020
Synonyms or Alternate Spellings:
  • Amyoplasia congenita (AC)
  • Amyoplasia multiplex congenita
  • Amyoplasia multiplex congenita (AMC)

ADVERTISEMENT: Supporters see fewer/no ads

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.