Angioimmunoblastic T cell lymphoma

Angioimmunoblastic T-cell lymphoma (AITL) is a rare, aggressive (fast-growing) form of peripheral T-cell lymphoma. It only accounts for around 1-2% of all non-Hodgkin lymphoma. It is one of the more common subtypes of mature T-cell lymphomas. 

Epidemiology

It can be more common in the elderly.

Clinical presentation

The clinical spectrum includes high fevers, generalised lymphadenopathy, a skin rash, and hepatosplenomegaly. 

Treatment and prognosis

Despite advances in treatment regimens for AITL, prognosis remains poor with an overall 5-year median survival of 32%. 3

Lymphoma
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Article information

rID: 35222
System: Haematology
Synonyms or Alternate Spellings:
  • AITL
  • Angioimmunoblastic T-cell lymphoma (AITL)
  • Angioimmunoblastic T-cell lymphoma (AIL)
  • Immunoblastic lymphadenopathy–like T-cell lymphoma

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