Citation, DOI, disclosures and article data
Citation:
Weerakkody Y, Bell D, Bickle I, Angiotensin converting enzyme. Reference article, Radiopaedia.org (Accessed on 13 Jan 2025) https://doi.org/10.53347/rID-74478
Angiotensin converting enzyme (ACE) is a central component of the renin-angiotensin system (RAS) which assists in blood pressure control by regulating the volume of fluids in the body.
Normal individuals may have a small volume of the angiotensin converting enzyme circulating in their blood.
Measurement
Angiotensin converting enzyme is normally measured in nanomoles per milliliter per minute (nmol/mL/min) with normal range considered less than than 40 nmol/mL/min. Elevated levels may be associated with a number of conditions with the most notable being sarcoidosis 4.
Other conditions that have reported to be associated with higher levels of angiotensin converting enzyme include:
-
1. Danilov SM, Tikhomirova VE, Metzger R, Naperova IA, Bukina TM, Goker-Alpan O, Tayebi N, Gayfullin NM, Schwartz DE, Samokhodskaya LM, Kost OA, Sidransky E. ACE phenotyping in Gaucher disease. (2018) Molecular genetics and metabolism. 123 (4): 501-510. doi:10.1016/j.ymgme.2018.02.007 - Pubmed
-
2. Lieberman J, Rea TH. Serum angiotensin-converting enzyme in leprosy and coccidioidomycosis. (1977) Annals of internal medicine. 87 (4): 423-5. doi:10.7326/0003-4819-87-4-422 - Pubmed
-
3. Albayrak M, Celebi H, Albayrak A, Sayilir A, Yesil Y, Balcik OS, Yokus O, Celik T. Elevated serum angiotensin converting enzyme levels as a reflection of bone marrow renin-angiotensin system activation in multiple myeloma. (2012) Journal of the renin-angiotensin-aldosterone system : JRAAS. 13 (2): 259-64. doi:10.1177/1470320312437070 - Pubmed
-
4. Csongrádi A, Enyedi A, Takács I, Végh T, Mányiné IS, Pólik Z, Altorjay IT, Balla J, Balla G, Édes I, Kappelmayer J, Tóth A, Papp Z, Fagyas M. Optimized angiotensin-converting enzyme activity assay for the accurate diagnosis of sarcoidosis. (2018) Clinical chemistry and laboratory medicine. 56 (7): 1117-1125. doi:10.1515/cclm-2017-0837 - Pubmed
Promoted articles (advertising)
Unable to process the form. Check for errors and try again.