Citation, DOI, disclosures and article data
Citation:
Kecler-Pietrzyk A, Knipe H, Bell D, et al. Anterior resection syndrome. Reference article, Radiopaedia.org (Accessed on 24 Mar 2025) https://doi.org/10.53347/rID-74105
Disclosures:
At the time the article was last revised Henry Knipe had the following disclosures:
- Integral Diagnostics, Shareholder (ongoing)
- Micro-X Ltd, Shareholder (ongoing)
These were assessed during peer review and were determined to
not be relevant to the changes that were made.
View Henry Knipe's current disclosures
Anterior resection syndrome refers to a wide spectrum of symptoms that develop following sphincter-preserving anterior resection of the rectum.
There have been reports that ~50% of patients who undergo anterior resection for rectal cancer develop anterior resection syndrome 2.
Risk factors
Risk factors for developing anterior resection syndrome include 4,5:
Symptoms include but are not limited to:
MRI of the pelvis, including dynamic sequences, is recommended to exclude other causes for altered bowel function.
Treatment and prognosis
In rare cases the symptoms are so severe that colostomy formation is performed.
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1. Bryant C, Lunniss P, Knowles C, Thaha M, Chan C. Anterior Resection Syndrome. Lancet Oncol. 2012;13(9):e403-8. doi:10.1016/s1470-2045(12)70236-x - Pubmed
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2. Carrillo A, Enríquez-Navascués J, Rodríguez A et al. Incidencia Y Caracterización Del Síndrome De Resección Anterior De Recto Mediante La Utilización De La Escala LARS (Low Anterior Resection Score). Cirugía Española. 2016;94(3):137-43. doi:10.1016/j.ciresp.2015.11.005 - Pubmed
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3. Colorectal Cancer. ISBN: 9781473136571 - Google Books
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4. Croese A, Lonie J, Trollope A, Vangaveti V, Ho Y. A Meta-Analysis of the Prevalence of Low Anterior Resection Syndrome and Systematic Review of Risk Factors. Int J Surg. 2018;56:234-41. doi:10.1016/j.ijsu.2018.06.031 - Pubmed
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5. Sun R, Dai Z, Zhang Y, Lu J, Zhang Y, Xiao Y. The Incidence and Risk Factors of Low Anterior Resection Syndrome (LARS) After Sphincter-Preserving Surgery of Rectal Cancer: A Systematic Review and Meta-Analysis. Support Care Cancer. 2021;29(12):7249-58. doi:10.1007/s00520-021-06326-2 - Pubmed
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6. Nicotera A, Falletto E, Arezzo A, Mistrangelo M, Passera R, Morino M. Risk Factors for Low Anterior Resection Syndrome (LARS) in Patients Undergoing Laparoscopic Surgery for Rectal Cancer. Surg Endosc. 2022;36(8):6059-66. doi:10.1007/s00464-021-09002-y - Pubmed
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