The anterior spinothalamic tract, also known as the ventral spinothalamic fasciculus, is an ascending pathway located anteriorly within the spinal cord, primarily responsible for transmitting coarse touch and pressure.
The lateral spinothalamic tract (discussed separately), in contrast, primarily transmits pain and temperature.
First-order neurones, whose cell bodies are in the dorsal root ganglion and whose axons extend from peripheral receptors, enter the cord via dorsal nerve roots.
The aforementioned first-order neurones synapse with second-order neurones whose bodies are located in the ipsilateral dorsal horn of the cord. In contrast to the lateral spinothalamic tract, whose fibers decussate almost immediately, these second-order neurones' axons ascend a few levels before crossing via the anterior spinal commissure and form the anterior spinothalamic tract 1-4.
The anterior spinothalamic tract lies in the anterior funiculus, medial to where the ventral spinal roots exit. It overlaps the vestibulospinal tract. Fibers of this tract are somatotopically organised for their entire course.
At the lower brainstem, the anterior tract joins the medial lemniscus. The neurones of the spinothalamic tract terminate in the ventral posterior nucleus of the thalamus after ascent. Here, they synapse with third-order neurones. These neurones project to the primary somatosensory area on the ipsilateral side of the cerebral cortex.
- 1. Tortora GJ, Derrickson BH. Principles of anatomy and physiology. Wiley. ISBN:0470084715. Read it at Google Books - Find it at Amazon
- 2. DSc SSP. Gray's anatomy. Churchill Livingstone. ISBN:0443066841. Read it at Google Books - Find it at Amazon
- 3. Ellis H. Clinical Anatomy. Wiley-Blackwell. ISBN:1405138041. Read it at Google Books - Find it at Amazon
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