Anti melanoma differentiation associated gene 5 (MDA5) antibody positive clinically amyopathic dermatomyositis
Citation, DOI, disclosures and article data
Citation:
Weerakkody Y, Bickle I, Anti melanoma differentiation associated gene 5 (MDA5) antibody positive clinically amyopathic dermatomyositis. Reference article, Radiopaedia.org (Accessed on 20 Jan 2025) https://doi.org/10.53347/rID-68912
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rID:
68912
Article created:
Disclosures:
At the time the article was created Yuranga Weerakkody had no recorded disclosures.
View Yuranga Weerakkody's current disclosures
Last revised:
Disclosures:
At the time the article was last revised Ian Bickle had no recorded disclosures.
View Ian Bickle's current disclosures
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2 contributors -
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Systems:
Synonyms:
- Anti melanoma differentiation associated gene 5 (mda5) antibody positive clinically amyopathic dermatomyositis (CADM)
- Anti-melanoma differentiation-associated gene 5 (MDA5) antibody-positive clinically amyopathic dermatomyositis
- Anti-MDA5 antibody-positive amyopathic dermatomyositis
Anti-MDA5 antibody-positive amyopathic dermatomyositis is a subtype of dermatomyositis where there is positivity to an anti-melanoma differentiation-associated gene 5 (MDA5) antibody. It has been reported to be associated with rapidly progressive interstitial lung disease (RP-ILD) resulting in high mortality. On thoracic imaging, patient's may show rapidly progressive interstitial changes (sometimes associated with pneumomediastinum +/- pneumothoraces) and have respiratory failure.
References
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