Anti-RO52 antibodies
Citation, DOI, disclosures and article data
Citation:
Weerakkody Y, Anti-RO52 antibodies. Reference article, Radiopaedia.org (Accessed on 24 Mar 2025) https://doi.org/10.53347/rID-164751
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rID:
164751
Article created:
Disclosures:
At the time the article was created Yuranga Weerakkody had no financial relationships to ineligible companies to disclose.
View Yuranga Weerakkody's current disclosures
Last revised:
Disclosures:
At the time the article was last revised Yuranga Weerakkody had no financial relationships to ineligible companies to disclose.
View Yuranga Weerakkody's current disclosures
Revisions:
2 times, by
1 contributor -
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Systems:
Synonyms:
- Anti ro52
Anti-Ro52 antibodies are a form of antibodies which are associated with distinct clinical manifestations.
They target a protein called TRIM21 protein and can occur in a variety of connective tissue diseases (CTD) which include anti-Ro52-positive antisynthetase syndrome and with lung considered an important target organ 2.
References
- 1. Zhu Y, Tang B, Kang M, Xiao Q. Anti-Ro52-Positive Antisynthetase Syndrome (ASS): A Case Report and Review of the Literature. Ann Transl Med. 2022;10(6):383. doi:10.21037/atm-22-787 - Pubmed
- 2. Wu S, Tang X, Wu L, Lu L, Feng X. Anti-Ro52 Antibodies in Clinical Practice: A Single-Centre Experience. Int J Clin Pract. 2021;75(3):e13679. doi:10.1111/ijcp.13679 - Pubmed
- 3. Oke V & Wahren-Herlenius M. The Immunobiology of Ro52 (TRIM21) in Autoimmunity: A Critical Review. J Autoimmun. 2012;39(1-2):77-82. doi:10.1016/j.jaut.2012.01.014 - Pubmed
- 4. Palmucci S, Galioto F, Fazio G et al. Clinical and Radiological Features of Lung Disorders Related to Connective-Tissue Diseases: A Pictorial Essay. Insights Imaging. 2022;13(1):108. doi:10.1186/s13244-022-01243-2 - Pubmed