Anti SRP autoantibody associated interstitial lung disease

Last revised by Dr Daniel J Bell on 10 Jul 2022

Anti SRP autoantibody associated interstitial lung disease is a form of autoimmune related interstitial lung disease.

It is thought to usually present with mild respiratory symptoms although some patients have been reported to have severe disease 1.

It is reported to occur as an extraskeletal manifestation of a myopathy such as immune-mediated necrotizing myopathy.

  • anti-SRP antibodies may be elevated.

Reported imaging literature is sparse at time of writing (2022) but with limited reports mostly suggesting an NSIP-type picture 1,2. Some patients have been reported to show an organizing pneumonia-type pattern 2.

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