Antopol-Goldman lesions are very rare presentations of subepithelial haemorrhage in the renal pelvis, presenting as discrete mass-like haematomas.
The cause of these lesions is uncertain, although long-term anticoagulation, non-steroidal anti-inflammatory drug (NSAID) overuse, trauma, and amyloidosis have been implicated.
Nonspecific mass-like lesion in the renal pelvis, with an attenuation greater than water (>10 HU). It does not enhance after administration of IV contrast.
The problem with Antopol-Goldman lesions is that their discrete appearance is likely to be confused with a renal neoplasm. Unfortunately, they are almost always diagnosed after nephrectomy.
- 1. Antopol W, Goldman L. Subepithelial hemorrhage of renal pelvis simulating neoplasm. Urol Cutaneous Rev. 2008;52 (4): 189-95. Pubmed citation
- 2. Levitt S, Waisman J, deKernion J. Subepithelial hematoma of the renal pelvis (Antopol-Goldman lesion): a case report and review of the literature. J. Urol. 1984;131 (5): 939-41. Pubmed citation
- 3. Demirkan NC, Tuncay L, Düzcan E et-al. Subepithelial haematoma of the renal pelvis (Antopol-Goldman lesion). Histopathology. 1999;35 (3): 282-3. Pubmed citation
- 4. Hammond NA, Lostumbo A, Adam SZ et-al. Imaging of adrenal and renal hemorrhage. Abdom Imaging. 2015;40 (7): . doi:10.1007/s00261-015-0453-5 - Pubmed citation