Antopol-Goldman lesion

Last revised by Daniel J Bell on 24 Feb 2019

Antopol-Goldman lesions are very rare presentations of subepithelial hemorrhage in the renal pelvis, presenting as discrete mass-like hematomas.


The cause of these lesions is uncertain, although long-term anticoagulation, non-steroidal anti-inflammatory drugs (NSAIDs) overuse, trauma, and amyloidosis have been implicated.

Radiographic features


Non-specific mass-like lesion in the renal pelvis, with an attenuation greater than water (>10 HU). It does not enhance after administration of IV contrast.

Differential diagnosis

The problem with Antopol-Goldman lesions is that their discrete appearance is likely to be confused with a renal neoplasm. Unfortunately, they are almost always diagnosed after nephrectomy.

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