The Appleby procedure is a type of pancreatic cancer resection.
For some patients with pancreatic cancer involving the body and tail of the pancreas, involvement of the celiac axis is a classic contraindication to pancreaticoduodenectomy (Whipple procedure).
With the Appleby procedure, there is a distal pancreatectomy with en bloc resection of the celiac axis. After the procedure, the hepatic blood supply is supplied entirely through the gastroduodenal artery.
The procedure is used in some centers with carefully selected patients.
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