Arachnoid granulation

Changed by Ayush Goel, 7 Nov 2014

Updates to Article Attributes

Body was changed:

An arachnoidArachnoid granulation (also known as a Pacchionian granulation) most frequently occurs in a parasagittal location and can cause an osteolytic, sharply circumscribed lucency on a skull x-rays, or a filling defect in dural venous sinuses, which can be mistaken for dural venous thrombosis. They increase in size with age and are seen in approximately two-thirds of patients.

Radiographic features

MRI

Signal characteristics are generally those of CSF 2

  • T1 -: low signal intensity
  • T2 -: high signal intensity; iso- to even slightly hyper-intensehyperintense to CSF
  • FLAIR -: should attenuate
  • T1 C+(Gd) -: no enhancement

EtymologyHistory and etymology

It is named after Antonio Pacchioni an Italian anatomist (1665-1726), who wrote extensively on the anatomy of the dura mater, published in 1705.

  • -<p>An <strong>arachnoid granulation</strong> (also known as a <strong>Pacchionian granulation</strong>) most frequently occurs in a parasagittal location and can cause an osteolytic, sharply circumscribed lucency on a skull x-rays, or a filling defect in dural venous sinuses, which can be mistaken for <a href="/articles/dural_venous_sinus_thrombosis">dural venous thrombosis</a>. They increase in size with age and are seen in approximately two-thirds of patients.</p><h4>Radiographic features</h4><h5>MRI</h5><p>Signal characteristics are generally those of CSF <sup>2</sup>: </p><ul>
  • +<p><strong>Arachnoid granulation</strong> (also known as a <strong>Pacchionian granulation</strong>) most frequently occurs in a parasagittal location and can cause an osteolytic, sharply circumscribed lucency on a skull x-rays, or a filling defect in dural venous sinuses, which can be mistaken for <a href="/articles/dural-venous-sinus-thrombosis">dural venous thrombosis</a>. They increase in size with age and are seen in approximately two-thirds of patients.</p><h4>Radiographic features</h4><h5>MRI</h5><p>Signal characteristics are generally those of CSF <sup>2</sup>: </p><ul>
  • -<strong>T1 -</strong> low signal intensity</li>
  • +<strong>T1:</strong> low signal intensity</li>
  • -<strong>T2 -</strong> high signal intensity; iso- to even slightly hyper-intense to CSF</li>
  • +<strong>T2:</strong> high signal intensity; iso- to even slightly hyperintense to CSF</li>
  • -<strong>FLAIR -</strong> should attenuate</li>
  • +<strong>FLAIR:</strong> should attenuate</li>
  • -<strong>T1 C+(Gd) -</strong> no enhancement</li>
  • -</ul><h4>Etymology</h4><p>It is named after <strong>Antonio Pacchioni</strong> an Italian anatomist (1665-1726), who wrote extensively on the anatomy of the <a href="/articles/dura-mater">dura mater</a>, published in 1705.</p>
  • +<strong>T1 C+(Gd):</strong> no enhancement</li>
  • +</ul><h4>History and etymology</h4><p>It is named after <strong>Antonio Pacchioni</strong> an Italian anatomist (1665-1726), who wrote extensively on the anatomy of the <a href="/articles/dura-mater">dura mater</a>, published in 1705.</p>

References changed:

  • 3. Lu CX, Du Y, Xu XX et-al. Multiple occipital defects caused by arachnoid granulations: Emphasis on T2 mapping. World J Radiol. 2012;4 (7): 341-4. <a href="http://dx.doi.org/10.4329/wjr.v4.i7.341">doi:10.4329/wjr.v4.i7.341</a> - <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419866">Free text at pubmed</a> - <a href="http://www.ncbi.nlm.nih.gov/pubmed/22900137">Pubmed citation</a><span class="auto"></span>
  • 5. Lu CX, Du Y, Xu XX et-al. Multiple occipital defects caused by arachnoid granulations: Emphasis on T2 mapping. World J Radiol. 2012;4 (7): 341-4. <a href="http://dx.doi.org/10.4329/wjr.v4.i7.341">doi:10.4329/wjr.v4.i7.341</a> - <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419866">Free text at pubmed</a> - <a href="http://www.ncbi.nlm.nih.gov/pubmed/22900137">Pubmed citation</a><span class="auto"></span>
  • 3. <a href="http://www.appliedradiology.com/case/case.asp?ID=587&amp;SubCatID=101&amp;CatID=43&amp;ThreadID=" title="http://www.appliedradiology.com/case/case.asp?ID=587&amp;SubCatID=101&amp;CatID=43&amp;ThreadID=" class="external text" rel="nofollow">Applied Radiology online</a>

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