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Citation:
Weerakkody Y, Bell D, Saber M, et al. Askin tumor. Reference article, Radiopaedia.org (Accessed on 09 Dec 2024) https://doi.org/10.53347/rID-7348
The original description of the Askin tumor (by Askin and Rosai in 1979 1), and many studies following it have led to a great deal of confusion. An Askin tumor was considered a separate entity or as a type of peripheral primitive neuroectodermal tumor, usually of the chest wall.
However, in the early 2000s, genetic research concluded that an Askin tumor is the same as a Ewing sarcoma, and now is part of the spectrum of the Ewing sarcoma family of tumors, sharing similar demographics, imaging findings and prognosis 2,3. Please see Ewing sarcoma of the chest wall for more detail.
While histologically the tumors are similar to an Ewing sarcoma, their typical location and growth pattern make the tumor a distinct radiographic entity.
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1. Askin FB, Rosai J, Sibley RK et-al. Malignant small cell tumor of the thoracopulmonary region in childhood: a distinctive clinicopathologic entity of uncertain histogenesis. Cancer. 1979;43 (6): 2438-51. [pubmed citation]
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2. Tateishi U, Gladish G, Kusumoto M et al. Chest Wall Tumors: Radiologic Findings and Pathologic Correlation: Part 2. Malignant Tumors. Radiographics. 2003;23(6):1491-508. doi:10.1148/rg.236015527 - Pubmed
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3. Iwamoto Y. Diagnosis and treatment of Ewing's sarcoma. Jpn. J. Clin. Oncol. 2007;37 (2): 79-89. doi:10.1093/jjco/hyl142 [pubmed citation]
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