Question 325
{"accessible":false,"alternatives":[{"id":1586,"text":"arose from a pre-existing low grade astrocytoma"},{"id":1587,"text":"had more than one enhancing nodular components"},{"id":1588,"text":"occurred after radiotherapy for another cranial tumor"},{"id":1589,"text":"regrew after successful resection or a prior glioblastoma"},{"id":1590,"text":"spread from a systemic primary malignancy"}],"archived":false,"correctAlternativeId":1586,"explanation":"\u003cp\u003eSecondary glioblastomas were considered tumors that arise from pre-existing lower-grade astrocytomas. As of the 2021 5th Edition WHO Classification of CNS tumors, they are essentially equivalent to grade 4 astrocytomas IDH mutant.\u0026nbsp;\u003c/p\u003e","id":325,"imageUrl":null,"imageAttribution":null,"imageAttributionCaseInfo":null,"firstQuestionPath":"/questions/2846","nextQuestionPath":"/articles/astrocytoma-idh-mutant-1/questions/75","relatedArticles":[{"id":4910,"title":"Glioblastoma, IDH-wildtype","link":"/articles/glioblastoma-idh-wildtype?lang=us"}],"alsoUsedIn":[],"stem":"\u003cp\u003eHistorically,\u0026nbsp;secondary glioblastomas were considered to be\u0026nbsp;tumors that...\u003c/p\u003e","menuLinks":[{"text":"Report problem with question","url":"https://docs.google.com/forms/d/e/1FAIpQLSfO3soWYhOjJ7yErSysyCe5V4A1CqW7WK3rDA7MtAkecMGqNw/viewform?entry.1624461248\u0026entry.553583435=https://radiopaedia.org/questions/325"}],"attemptsPercentages":[{"alternativeId":"1587","percentage":3},{"alternativeId":"1589","percentage":5},{"alternativeId":"1590","percentage":3},{"alternativeId":"1588","percentage":14},{"alternativeId":"1586","percentage":75}],"promptToLogin":false,"questionManager":false,"articleId":"astrocytoma-idh-mutant"}