Atypical ductal hyperplasia

Dr Henry Knipe and Radswiki et al.

Atypical ductal hyperplasia (ADH) is a histologically borderline lesion that has some, but not all the features of ductal carcinoma in situ (DCIS). Sometimes the distinction between ADH and DCIS is simply on the basis of the number of ducts involved. 

Pathology

Atypical ductal hyperplasia is a lesion with a lot of malignant potential. It lacks the strict criteria for ductal carcinoma in situ. A lesion which is qualitatively similar to DCIS yet quantitatively is inadequate (< 2 ducts involved) is termed as atypical ductal hyperplasia 3

Treatment and prognosis

ADH is considered a high risk breast lesion. Therefore surgical excision is advised as under-estimation of ductal carcinoma in situ is encountered when atypical ductal hyperplasia is retrieved on a large core needle biopsy (up to one-third of cases may be upstaged to DCIS).


Breast imaging and pathology
Share Article

Article Information

rID: 12683
Systems: Breast, Oncology
Section: Pathology
Synonyms or Alternate Spellings:
  • Atypical ductal hyperplasia (ADH)

Support Radiopaedia and see fewer ads

Updating… Please wait.
Loadinganimation

Alert accept

Error Unable to process the form. Check for errors and try again.

Alert accept Thank you for updating your details.