Babinski-Nageotte syndrome is thought to be a brainstem stroke syndrome in between that of the hemimedullary syndrome (Reinhold syndrome) and the lateral medullary syndrome (Wallenberg syndrome) 1,2. It is considered to be a spreading of the “Wallenbergian” lateral lesion, often due to occlusion of intracranial portion of the vertebral artery followed by PICA and its branches, to the corticospinal pathway resulting in the lateral medullary syndrome with contralateral hemiparesis/hemiplegia 1,2.
In many texts this eponymous syndrome is incorrectly attributed to actually being the hemimedullary syndrome, however this is a very similar yet clinically distinct syndrome 2.
History and etymology
The syndrome was first described by Joseph Babinski (1858-1932) and Jean Nageotte (1866-1948), French physicians, in 1902 3.
- 1. Krasnianski M, Müller T, Stock K, Zierz S. Between Wallenberg syndrome and hemimedullary lesion: Cestan-Chenais and Babinski-Nageotte syndromes in medullary infarctions. Journal of neurology. 253 (11): 1442-6. doi:10.1007/s00415-006-0231-3 - Pubmed
- 2. Ropper AH, Samuels MA, Klein JP. Adams and Victor's principles of neurology 10th ed. New York: McGraw-Hill Medical Pub. Division; 2014.
- 3. Babinski J, Nageotte J. Hemiasynergie, lateropulsion et myosis bulbaires avec hemianesthesie et hemiplegie croisees. Rev Neurol (Paris). 1902;10:358-65.