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Citation:
Feger J, Haouimi A, Backfill. Reference article, Radiopaedia.org (Accessed on 05 Dec 2024) https://doi.org/10.53347/rID-89665
Backfill refers to intra-articular high signal intensity on T1 weighted images seen in axial spondylarthritis within the sacroiliac joint filling up excavated bone erosions 1. It has been characterized as a complete loss of the cortical bone within the sacroiliac joint at the anticipated location either on the sacral or iliac side replaced by high-signal intensity tissue on T1-weighted images clearly definable from the adjacent normal bone marrow signal by the irregular signal from the sclerotic border of the erosion 1,2. The histopathological correlate of this MRI feature is not yet clear 1. Backfill has been associated with the resolution of joint inflammation and the decline of bone erosions and is thought to represent new bone formation or synovial metaplasia 3,4. It has been shown to be of a very high diagnostic value for axial spondylarthritis with a high specificity 5.
See also
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1. Maksymowych W, Wichuk S, Chiowchanwisawakit P, Lambert R, Pedersen S. Fat Metaplasia and Backfill Are Key Intermediaries in the Development of Sacroiliac Joint Ankylosis in Patients with Ankylosing Spondylitis. Arthritis Rheumatol. 2014;66(11):2958-67. doi:10.1002/art.38792
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2. Maksymowych W, Wichuk S, Dougados M et al. MRI Evidence of Structural Changes in the Sacroiliac Joints of Patients with Non-Radiographic Axial Spondyloarthritis Even in the Absence of MRI Inflammation. Arthritis Res Ther. 2017;19(1):126. doi:10.1186/s13075-017-1342-9
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3. Laloo F, Herregods N, Jaremko J et al. MRI of the Axial Skeleton in Spondyloarthritis: The Many Faces of New Bone Formation. Insights Imaging. 2019;10(1):67. doi:10.1186/s13244-019-0752-4
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4. Jans L, Egund N, Eshed I, Sudoł-Szopińska I, Jurik A. Sacroiliitis in Axial Spondyloarthritis: Assessing Morphology and Activity. Semin Musculoskelet Radiol. 2018;22(2):180-188. doi:10.1055/s-0038-1639470
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5. Laloo F, Herregods N, Varkas G et al. MR Signal in the Sacroiliac Joint Space in Spondyloarthritis: A New Sign. Eur Radiol. 2017;27(5):2024-2030. doi:10.1007/s00330-016-4587-9
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