Bariatric embolization

Last revised by Dr Henry Knipe on 05 Sep 2020

Bariatric embolization is an interventional procedure performed with a view to inducing weight-loss in the treatment of obesity. Evidence from clinical trials suggests that the procedure is well tolerated and has a good safety profile. Early studies demonstrate a mild-moderate beneficial effect. However, further research is required to establish the efficacy of this treatment.

Most commonly this is performed via the splenic artery and selecting the left gastro-epiploic artery where the embolic agent (commonly microspheres) may be distributed. 

Preliminary studies of animal models 2,3 demonstrate histopathological evidence that the procedure reduces local ghrelin production which may serve as the underlying endocrine mechanism for weight loss.

 

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