Basal cell carcinoma

A basal cell carcinoma (BCC) is one of the commonest non-melanocytic types of skin cancer

Typically present in elderly fair skinned patients in the 7th to 8th decades of life. There may be an increased male predilection.

Multiple basal cell carcinomas may be present in those with Gorlin-Goltz syndrome.

It is an indolent primary cutaneous neoplasm arising from the basal layer of the epidermis.

Generally reported signal characteristics include 1

  • T1: isointense or hyperintense (relative to muscle)
  • T2: hyperintense (relative to muscle)
  • T1 C+(Gd): enhances 

It is often locally aggressive, may invade the skin and adjacent structures, including the muscles and bones. It has a low metastatic potential (but can very rarely metastasize). It also has high rate of recurrence. 

Surgery is the treatment of choice of primary basal cell cancers; chemotherapy (e.g. sonidegib (OdomzoTM) is used for metastatic cases.

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Article information

rID: 72322
Synonyms or Alternate Spellings:
  • BCC
  • Basal cell carcinomas (BCCs)
  • Basal cell carcinomas
  • Basal cell carcinoma (BCC)

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Cases and figures

  • Case 1: peri-orbital
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  • Case 2: nasal region
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  • Case 3: periocular with orbital invasion
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