Basivertebral nerve

Last revised by Dr Daniel J Bell on 12 Jul 2022

The basivertebral nerve supplies the vertebral endplates and can be a target for treating back pain. 

Gross anatomy

The basivertebral nerve is a paired nerve arising from the sinuvertebral nerve. It ascends from its origin to enter the spinal canal, traversing centrally 1. It courses with the basivertebral vessels into the central vascular foramen. Within the foramen, it travels approximately 1/3 the diameter of the vertebral body before forming a trunk cluster and branching cranially and caudally. It provides sensation to the vertebral end plates, which form the superior and inferior edges of the vertebral body 2-4.

Clinical importance

Vertebral endplates are highly susceptible to injury and are the source of most chronic lower back pain 2. The basivertebral nerve provides an important role in nociceptive pain transmission for these endplates and is, therefore, a target for therapeutic ablation. The procedure is a minimally invasive spinal procedure that targets the nerve as it enters the central vascular foramen 1,3

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