Benedikt syndrome

Dr Henry Knipe and Dr Bruno Di Muzio et al.

Benedikt syndrome, or paramedian midbrain syndrome, is a midbrain stroke syndrome that involves the fascicles of the oculomotor nerve and the red nucleus resulting in an ipsilateral CN III palsy and crossed hemiataxia and choreoathetosis 1-4.

Using imaging alone, it is difficult to distinguish Benedikt from Weber syndrome, unless clear involvement of the red nucleus can be identified, which is seen in the former 1-4.

History and etymology

The syndrome was first described by Moritz Benedikt (1835-1920), a Hungarian-Austrian neurologist, in 1889 5.

Stroke and intracranial haemorrhage
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Article information

rID: 31290
Section: Syndromes
Synonyms or Alternate Spellings:
  • Paramedian midbrain syndrome
  • Benedikt's syndrome

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