Benedikt syndrome

Last revised by Dr Mostafa El-Feky on 29 Jul 2022

Benedikt syndrome, or paramedian midbrain syndrome, is a midbrain stroke syndrome that involves the fascicles of the oculomotor nerve and the red nucleus.

It is usually caused by an ischemic stroke, typically involving branches of the posterior cerebral artery 1-4

Using imaging alone, it is difficult to distinguish Benedikt syndrome from Weber syndrome, unless clear involvement of the red nucleus can be identified, which is seen in the former 1-4.

The syndrome was first described by Moritz Benedikt (1835-1920), a Hungarian-Austrian neurologist, in 1889 5.

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Cases and figures

  • Case 1
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