Bickers Adams Edwards syndrome is a rare x-linked disorder with profound mental retardation, adducted thumb and large head which is comprising of a constellation of congenital CNS anomalies including :
- congenital aqueductal stenosis
- corpus callosum agenesis
- absence of the medullary pyramids
- corticospinal tracts agenesis
Genetic counseling is recommended due high rate of disease in following pregnancies.
- 1. Peter P. Urban and Louis R Caplan. Brainstem Disorders. Springer; 1st Edition. edition (September 27, 2011)