Bilateral adrenal gland enlargement
Last revised by Mostafa Elfeky on 13 Oct 2021
Citation, DOI, disclosures and article data
Citation:
Gaillard F, Elfeky M, Baba Y, et al. Bilateral adrenal gland enlargement. Reference article, Radiopaedia.org (Accessed on 19 Apr 2024) https://doi.org/10.53347/rID-10200
rID:
10200
Article created:
Disclosures:
At the time the article was created Frank Gaillard had no recorded disclosures.
View Frank Gaillard's current disclosures
Last revised:
13 Oct 2021,
Mostafa Elfeky ◉
Disclosures:
At the time the article was last revised Mostafa Elfeky had no recorded disclosures.
View Mostafa Elfeky's current disclosures
Revisions:
14 times, by
13 contributors -
see full revision history and disclosures
Systems:
Sections:
Tags:
Synonyms:
- Large adrenal glands - bilateral
- Bilateral enlarged adrenal glands
- Bilateral adrenomegaly
- Bilateral adrenal enlargement
The differential for bilaterally enlarged adrenal glands (adrenomegaly) is relatively limited:
- adrenal hyperplasia
- adrenal metastases
- adrenal hemorrhage
- venous infarction of the adrenal glands
-
adrenal involvement with granulomatous diseases
- adrenal histoplasmosis 5,6
- adrenal lymphoma
- primary pigmented nodular adrenal dysplasia (PPNAD): usually the glands are normal in size, but nodular; in older patients they may be enlarged 1
- adrenal pheochromocytoma: especially when familial (e.g. in multiple endocrine neoplasia type II) 4
References
- 1. Rockall AG, Babar SA, Sohaib SA et-al. CT and MR imaging of the adrenal glands in ACTH-independent cushing syndrome. Radiographics. 24 (2): 435-52. doi:10.1148/rg.242035092 - Pubmed citation
- 2. Doppman JL, Chrousos GP, Papanicolaou DA et-al. Adrenocorticotropin-independent macronodular adrenal hyperplasia: an uncommon cause of primary adrenal hypercortisolism. Radiology. 2000;216 (3): 797-802. Radiology (full text) - Pubmed citation
- 3. Doppman JL, Nieman LK, Travis WD et-al. CT and MR imaging of massive macronodular adrenocortical disease: a rare cause of autonomous primary adrenal hypercortisolism. J Comput Assist Tomogr. 15 (5): 773-9. - Pubmed citation
- 4. Townsend RR, McGinnis PA, Tuan WM, Thrasher K. Case report: bilateral adrenal pheochromocytoma. (1994) The American journal of the medical sciences. 308 (2): 123-5. Pubmed
- 5. D A Wilson, H G Muchmore, R G Tisdal, A Fahmy, J V Pitha. Histoplasmosis of the adrenal glands studied by CT. (1984) Radiology. 150 (3): 779-83. doi:10.1148/radiology.150.3.6695079 - Pubmed
- 6. Mukherjee, Jagat J., Villa, Michael L., Tan, Lenny, Lee, K. O.. Bilateral Adrenal Masses Due to Histoplasmosis. (2005) The Journal of Clinical Endocrinology & Metabolism. 90 (12): 6725. doi:10.1210/jc.2005-1868
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