Bilateral testicular lesions

Last revised by Ammar Ashraf on 25 Mar 2023

Bilateral testicular lesions have a relatively limited differential diagnosis. 

Differential diagnosis

Neoplastic 
  • lymphoblastic leukemia (acute or chronic)
  • lymphoma (non-Hodgkin's)
    • primary testicular lymphoma is rare but the testes are often the site of lymphoma/leukemia recurrence due to the chemotherapy inability to pass the blood–testes barrier
  • metastases
Non-neoplastic

See also 

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Cases and figures

  • Case 1: congenital AML with testicular relapse
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  • Case 2: testicular adrenal rest tumor (TART)
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