Blend sign (brain)
Last revised by Rohit Sharma ◉ on 24 Sep 2022
Citation, DOI & article data
Citation:
Brehmer M, Sharma R, Liu A, et al. Blend sign (brain). Reference article, Radiopaedia.org (Accessed on 02 Feb 2023) https://doi.org/10.53347/rID-42921
rID:
42921
Article created:
15 Feb 2016 by Moritz Brehmer
Revisions:
5 times by 5 users - see full revision history
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The blend sign refers to the appearance of intracranial hematoma in non-contrast CT brain. It is a strong predictor of early hematoma expansion in spontaneous intracerebral hemorrhages, which is a prognosticator for poor functional outcomes 1.
The blend sign is defined as 2:
- blending of a relatively hypodense area with an adjacent hyperdense area
- a well-defined margin identifiable by the naked eye
- at least 18 Hounsfield unit difference between the 2 areas
- the relatively hypodense area not being encapsulated by the hyperdense region
References
- 1. Zhang M, Chen J, Zhan C et al. Blend Sign Is a Strong Predictor of the Extent of Early Hematoma Expansion in Spontaneous Intracerebral Hemorrhage. Front Neurol. 2020;11:334. doi:10.3389/fneur.2020.00334 - Pubmed
- 2. Li Q, Zhang G, Huang Y et al. Blend Sign on Computed Tomography. Stroke. 2015;46(8):2119-23. doi:10.1161/strokeaha.115.009185
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