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Bone erosions or simply erosions refer to focal bony defects in the subchondral bone plate or cortical bone and the adjacent trabecular bone. Unlike bone cysts, the cortical or subchondral bone is also affected. They are a feature seen in inflammatory arthritides and erosive osteoarthritis and can also occur in crystal deposition disease, metabolic, autoimmune or other inflammatory disorders or tumors.
Contrary to scalloping erosions are characterized by a more active rapid bone loss 1.
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Bone erosions are bony defects developing as a result of excessive local bone resorption and inadequate bone formation 1,2. They are commonly associated with synovitis and osteitis 1.
Bone erosions can arise from a variety of causes which include the following 1-3:
- inflammatory arthritides
- crystal deposition disease
- septic arthritis (early stage of medullary involvement and osteomyelitis)
- Langerhans cell histiocytosis
Bone erosions are typically described in articular (central or marginal) and periarticular locations and can affect the subchondral bone plate or the cortical bone. This might happen in central subchondral locations of joints usually covered by articular cartilage, in the bare areas within the joints or outside of the joints at the entheses or other locations (e.g. tumor, metabolic).
The following types of bone erosions are described 3:
- subchondral or central bone erosions: typically seen in osteoarthritis
- marginal erosions: a typical feature of rheumatoid arthritis, seen in the bare area of joints
- erosions at the entheses: a typical feature of spondylarthritis
Bony erosions are characterized by small bony lucencies or breaks in the subchondral or cortical bony surface often associated with alterations of the adjacent trabecular bone 4.
Ultrasound has a better capability than radiographs in the detection of bone erosions 3-5, which can be nicely depicted as a bony surface discontinuity or defect visible in two different planes 3,6.
CT allows for a reliable evaluation of cortical bone and subchondral bone plate in multiple different planes at various locations and thus the detection of bony erosions.
Bone erosions are characterized by a loss of the dark signal or disruption of the subchondral bone plate or the cortical bone.
They can be readily visualized on MRI, which is considered as a very sensitive technique for their detection 2 also in joints, which are hardly or not accessible by ultrasound. Especially high-resolution thin slice sequences show a high sensitivity, which is considered comparable or superior to CT 7-9.
- T1: variable
- T2: hyperintense
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- 7. Egund N, Eshed I, Sudoł-Szopińska I, Jurik A, Jans L. Sacroiliitis in Axial Spondyloarthritis: Assessing Morphology and Activity. Semin Musculoskelet Radiol. 2018;22(02):180-8. doi:10.1055/s-0038-1639470 - Pubmed
- 8. Weber U, Pedersen S, Østergaard M, Rufibach K, Lambert R, Maksymowych W. Can Erosions on MRI of the Sacroiliac Joints Be Reliably Detected in Patients with Ankylosing Spondylitis? - A Cross-Sectional Study. Arthritis Res Ther. 2012;14(3):R124. doi:10.1186/ar3854 - Pubmed
- 9. Diekhoff T, Greese J, Sieper J, Poddubnyy D, Hamm B, Hermann K. Improved Detection of Erosions in the Sacroiliac Joints on MRI with Volumetric Interpolated Breath-Hold Examination (VIBE): Results from the SIMACT Study. Ann Rheum Dis. 2018;77(11):1585-9. doi:10.1136/annrheumdis-2018-213393 - Pubmed