Brain and Spinal Cord Injury Center score
Citation, DOI, disclosures and article data
At the time the article was created Francis Deng had no recorded disclosures.View Francis Deng's current disclosures
At the time the article was last revised Ali Alsmair had no recorded disclosures.View Ali Alsmair's current disclosures
The Brain and Spinal Injury Center (BASIC) score is a classification system for grading acute traumatic spinal cord injury based on the axial extent of intramedullary signal abnormality on T2 weighted MRI.
The BASIC score is an ordinal scale that is graded 0 to 4 1:
- BASIC 0 (normal): no cord signal abnormality
- BASIC 1 (grey matter only): T2 hyperintensity confined to grey matter
- BASIC 2 (some white matter): intramedullary T2 hyperintensity extends beyond expected grey matter margins to involve spinal white matter, but does not involve the entire transverse extent of the spinal cord
- BASIC 3 (all white matter in-plane): T2 hyperintensity involving the entire axial plane of the spinal cord
- BASIC 4 (with hemorrhage): grade 3 injury with the addition of foci of T2 hypointensity consistent with hemorrhage
BASIC score 0-2 injuries with hemorrhage are elevated by one grade 1.
The BASIC score correlates with neurological symptoms (ASIA Impairment Scale) as well as prognosis for short-term improvement 1-3 and ability to walk after a year 4.
The interrater agreement has been good or poor in different studies 1,5.
The BASIC score is one component of the US National Institute of Neurological Disorders and Stroke (NINDS) common data elements instrument for spinal cord injury research 5.
- 1. Talbott J, Whetstone W, Readdy W et al. The Brain and Spinal Injury Center Score: A Novel, Simple, and Reproducible Method for Assessing the Severity of Acute Cervical Spinal Cord Injury with Axial T2-Weighted MRI Findings. J Neurosurg Spine. 2015;23(4):495-504. doi:10.3171/2015.1.SPINE141033 - Pubmed
- 2. Haefeli J, Mabray M, Whetstone W et al. Multivariate Analysis of MRI Biomarkers for Predicting Neurologic Impairment in Cervical Spinal Cord Injury. AJNR Am J Neuroradiol. 2017;38(3):648-55. doi:10.3174/ajnr.A5021 - Pubmed
- 3. Mabray M, Talbott J, Whetstone W et al. Multidimensional Analysis of Magnetic Resonance Imaging Predicts Early Impairment in Thoracic and Thoracolumbar Spinal Cord Injury. J Neurotrauma. 2016;33(10):954-62. doi:10.1089/neu.2015.4093 - Pubmed
- 4. Berliner J, O'Dell D, Albin S et al. The Influence of Conventional T MRI Indices in Predicting Who Will Walk Outside One Year After Spinal Cord Injury. J Spinal Cord Med. 2021;:1-7. doi:10.1080/10790268.2021.1907676 - Pubmed
- 5. Fisher J, Krisa L, Middleton D et al. Validation of the National Institute of Neurological Disorders and Stroke Spinal Cord Injury MRI Common Data Elements Instrument. AJNR Am J Neuroradiol. 2021;42(4):787-93. doi:10.3174/ajnr.A7000 - Pubmed