Breast cancer metastases
Citation, DOI, disclosures and article data
At the time the article was created Jeremy Jones had no recorded disclosures.
View Jeremy Jones's current disclosuresAt the time the article was last revised Rania Adel Anan had no financial relationships to ineligible companies to disclose.
View Rania Adel Anan's current disclosures- Metastases from breast cancer
- Metastases from breast cancers
Metastases from breast cancer can be a frequent finding in routine oncoradiological practice.
Clinical presentation
With the universal use and acceptance of screening mammography, the isolated clinical presentation from metastases from breast carcinoma has become rare in clinical practice. Historically, presentation from metastases was much more common than it is now.
More commonly, the primary breast malignancy is known at the time the metastases are found. The commonly accepted dictum reads that the smaller the breast carcinoma, the less the chances of metastases.
In radiology practice, the most common presentation is an enlarged node in the axilla. Senology may or may not demonstrate a lesion in the ipsilateral breast. FNA of the node then shows metastatic adenocarcinoma cells.
Pathology
Location
Most common sites of metastases:
Less frequent sites of metastases are:
- liver
- brain
- pancreas 3,4
- intramammary (rare)
- uvea 5
- orbit: forming a retrobulbar extraconal mass lesion with desmoblastic reaction resulting in enophthalmos
- pericardium
- soft tissue: rare
Quiz questions
References
- 1. Glendenning J, Cook G. Imaging breast cancer bone metastases: current status and future directions. Semin Nucl Med. 2013;43 (4): 317-23. doi:10.1053/j.semnuclmed.2013.02.002 - Pubmed citation
- 2. Haaga JR, Boll D. CT and MRI of the whole body. Mosby. (2009) ISBN:0323053750. Read it at Google Books - Find it at Amazon
- 3. Scatarige JC, Horton KM, Sheth S et-al. Pancreatic parenchymal metastases: observations on helical CT. AJR Am J Roentgenol. 2001;176 (3): 695-9. doi:10.2214/ajr.176.3.1760695 - Pubmed citation
- 4. Bonapasta SA, Gregori M, Lanza R et-al. Metastasis to the Pancreas from Breast Cancer: Difficulties in Diagnosis and Controversies in Treatment. Breast Care (Basel).5 (3): 170-173. Free text at pubmed - Pubmed citation
- 5. Demirci H, Shields CL, Chao AN et-al. Uveal metastasis from breast cancer in 264 patients. (2003) American journal of ophthalmology. 136 (2): 264-71. doi:10.1016/s0002-9394(03)00192-2 - Pubmed
Incoming Links
- Thoracic corpectomy
- Breast cancer brain metastases
- Transcoelomic spread of breast cancer
- Spinal dural and leptomeningeal metastases
- Pulmonary metastases - cannon ball
- Breast cancer with brain and skull bone metastases
- Brain metastases from breast carcinoma
- Brain metastases from breast cancer
- Sclerotic metastases of the lumbosacral spine
- Skull metastasis
- Skull metastasis
- Breast cancer metastasis
- Breast cancer brain metastases
- Haemorrhagic intracranial metastases from breast cancer
- Orbital metastasis
- Metastatic breast cancer
- Pathological fracture - breast cancer bone metastasis
- Breast cancer with single liver metastasis
- Dural and vertebral metastases from breast cancer
- Multiple lung and mediastinal metastases from breast cancer
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