Bright rim sign (DNET)
Citation, DOI, disclosures and article data
Citation:
Gaillard F, Sharma R, Yap J, et al. Bright rim sign (DNET). Reference article, Radiopaedia.org (Accessed on 09 Dec 2024) https://doi.org/10.53347/rID-1017
Permalink:
rID:
1017
Article created:
Disclosures:
At the time the article was created Frank Gaillard had no recorded disclosures.
View Frank Gaillard's current disclosures
Last revised:
Disclosures:
At the time the article was last revised Rohit Sharma had no financial relationships to ineligible companies to disclose.
View Rohit Sharma's current disclosures
Revisions:
25 times, by
16 contributors -
see full revision history and disclosures
Systems:
Sections:
Synonyms:
- Bright rim sign - DNET
- Hyperintense rim sign in DNET
- Hyperintense rim sign in dysembryoplastic neuroepithelial tumours
The bright rim sign, also known as the hyperintense ring sign, is an MRI sign described most frequently in dysembryoplastic neuroepithelial tumours (DNET) but is also seen in some other tumours.
On this page:
Terminology
Although the sign is most associated with DNETs, and should probably be reserved in cases where DNET is the suspected diagnosis, it is also seen in other pathologies such as myxoid glioneuronal tumours 3.
It is also visually equivalent to T2/FLAIR mismatch sign seen in some astrocytomas, IDH-mutant.
Pathology
On pathologic examination, this bright rim sign corresponds to glioneuronal elements loosely packed at the margin of the tumour surrounding an area so replete with fluid that it partially suppresses on FLAIR 1.
Radiographic features
MRI
It is described as a well-defined rim of high signal around the DNET on FLAIR sequences. This FLAIR hyperintense ring, whether complete or incomplete, is fairly sensitive and specific for DNET 2. On postoperative imaging, this sign may be a helpful clue for residual tumour or tumour recurrence 2.
Quiz questions
{"containerId":"expandableQuestionsContainer","displayRelatedArticles":true,"displayNextQuestion":true,"displaySkipQuestion":true,"articleId":1017,"questionManager":null,"mcqUrl":"https://radiopaedia.org/articles/bright-rim-sign-dnet-1/questions/1799?lang=gb"}
References
- 1. Raz E, Kapilamoorthy TR, Gupta AK et-al. Case 186: Dysembrioplastic neuroepithelial tumor. (2012) Radiology. 265 (1): 317-20. doi:10.1148/radiol.12100118 - Pubmed
- 2. Parmar HA, Hawkins C, Ozelame R et-al. Fluid-attenuated inversion recovery ring sign as a marker of dysembryoplastic neuroepithelial tumors. (2007) Journal of computer assisted tomography. 31 (3): 348-53. doi:10.1097/01.rct.0000243453.33610.9d - Pubmed
- 3. Narvaez E, Inada B, de Almeida P et al. Myxoid Glioneuronal Tumour - Report of Three Cases of a New Tumour in a Typical Location and Review of Literature. BJR Case Rep. 2021;7(4):20200139. doi:10.1259/bjrcr.20200139 - Pubmed
Incoming Links
Articles:
Cases:
- Dysembryoplastic neuroepithelial tumour (DNET) associated with dysgenesis of the corpus callosum
- Dysembryoplastic neuroepithelial tumor
- Myxoid glioneuronal tumor
- Dysembryoplastic neuroepithelial tumour (DNET)
- Dysembryoplastic neuroepithelial tumour (DNET)
- Dysembryoplastic neuroepithelial tumour (DNET)
- DNET
- Dysembryoplastic neuroepithelial tumours (DNET)
- Dysembryoplastic neuroepithelial tumour (DNET)
- Dysembryoplastic neuroepithelial tumour
- Dysembryoplastic neuroepithelial tumor
- Dysembryoplastic neuroepithelial tumour (DNET)
- Dysembryoplastic neuroepithelial tumour (DNET)
- Dysembryoplastic neuroepithelial tumour
- Dysembryoplastic neuroepithelial tumour
- Dysembroplastic neuroectodermal tumours (DNET's): bilateral
- Dysembryoplastic neuroepithelial tumour (DNET)
- Dysembryoplastic neuroepithelial tumour
- Dysembryoplastic neuroepithelial tumour (DNET)
- Dysembryoplastic neuroepithelial tumour (DNET)
Multiple choice questions:
Related articles: Malformations of the central nervous system
-
malformations of cortical development
- abnormal cell proliferation or apoptosis
- abnormal brain size
-
microcephaly
- with normal to simplified cortical pattern
- microcephaly with lissencephaly
- microcephaly with extensive polymicrogyria
- macrocephalies (megalencephaly/macrocephaly)
-
microcephaly
- abnormal cell proliferation
- non-neoplastic
- cortical hamartomas of tuberous sclerosis
- hemimegalencephaly
-
focal cortical dysplasia (Type I and Type IIb)
- Palmini classification (2004)
- Barkovich classification (2005)
- Blumcke classification (2011)
- neoplastic
- non-neoplastic
- abnormal neuronal migration
- lissencephaly
- lissencephaly type I: subcortical band heterotopia spectrum (band heterotopia): undermigration
- lissencephaly type II (cobblestone complex)
- heterotopia: ectopic migration
- subependymal heterotopia
- subcortical heterotopia (not including band heterotopia)
- marginal glioneuronal heterotopia
- lissencephaly
- abnormal cortical organisation
- mild malformations of cortical development (previously microdysgenesis)
-
polymicrogyria and schizencephaly
- bilateral polymicrogyria syndromes
- schizencephaly
- focal cortical dysplasia (Type IIa)
- abnormal brain size
- not otherwise classified
- malformations secondary to inborn errors of metabolism
- mitochondrial and pyruvate metabolic disorders
- peroxisomal disorders
- other unclassified malformations
- malformations secondary to inborn errors of metabolism
- abnormal cell proliferation or apoptosis
-
midline abnormalities of the brain
- absent septum pellucidum
- cephaloceles
-
midline nasal region lesions
- nasal dermoid
- nasal glioma
- nasal dermal sinus
- cerebral hemispheres
-
holoprosencephaly/septo-optic dysplasia spectrum
- septo-optic dysplasia
- lobar holoprosencephaly
- semilobar holoprosencephaly
- alobar holoprosencephaly
- middle interhemispheric variant/syntelencephaly
-
holoprosencephaly/septo-optic dysplasia spectrum
- corpus callosum
- intracranial lipoma
-
malformations of the cerebellum
- cerebellar hypoplasia
- focal hypoplasia
- generalised hypoplasia
- with enlarged fourth ventricle
- normal fourth ventricle
- with normal pons
- with small pons
- normal foliation
- pontocerebellar hypoplasias of Barth, types I and II
- cerebellar hypoplasias, not otherwise specified
- normal foliation
- cerebellar dysplasia
- focal dysplasia
- isolated vermian dysplasia
- molar tooth malformations including Joubert syndrome
- rhombencephalosynapsis
- isolated hemispheric dysplasia
- focal cerebellar cortical dysplasias/heterotopia
- dysplastic cerebellar gangliocytoma
- isolated vermian dysplasia
- generalised dysplasia
- congenital muscular dystrophies
- cytomegalovirus
- lissencephaly with RELN mutation
- lissencephaly with agenesis of corpus callosum and cerebellar dysplasia
- associated with diffuse cerebral polymicrogyria
- diffusely abnormal foliation
- focal dysplasia
- cerebellar hypoplasia
- malformations of the brainstem
Unable to process the form. Check for errors and try again.