Citation, DOI and article data
Broca's area is located in the posterior inferior frontal gyrus (pars opercularis and pars triangularis) of the dominant hemisphere, anterior to the anterior commissure line. It is anterior to the primary motor cortex on the precentral gyrus.
- superior division of the middle cerebral artery (MCA)
This language-eloquent area is most often located in the left hemisphere, also in left-handed individuals 4. However, right-hemispheric dominance may occur in roughly 4% of right-handed individuals and may be as high as 27% in extreme left-handers 5.
Maybe even more interestingly, there appears to be significant plasticity of organization in the brain regarding the shift of language-eloquent hemisphere 5. This has recently been demonstrated to occur in right-handed patients under experimental conditions with left-sided (virtually reversible) perisylvian lesions by functional MRI (fMRI) 3.
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- 2. Naidich TP, Castillo M, Cha S et-al. Imaging of the Brain: Expert Radiology Series, 1e. Saunders. ISBN:1416050094. Read it at Google Books - Find it at Amazon
- 3. Krieg SM, Sollmann N, Hauck T et-al. Functional language shift to the right hemisphere in patients with language-eloquent brain tumors. PLoS ONE. 2013;8 (9): e75403. doi:10.1371/journal.pone.0075403 - Free text at pubmed - Pubmed citation
- 4. Daroff RB, Fenichel GM, Jankovic J et-al. Bradley's Neurology in Clinical Practice: Expert Consult - Online and Print, 6e. Saunders. ISBN:1437704344. Read it at Google Books - Find it at Amazon
- 5. Finger S, Buckner RL, Buckingham H. Does the right hemisphere take over after damage to Broca's area? the Barlow case of 1877 and its history. Brain Lang. 2003;85 (3): 385-95. Pubmed citation
- 6. Knecht S, Dräger B, Deppe M et-al. Handedness and hemispheric language dominance in healthy humans. Brain. 2001;123 Pt 12: 2512-8. Pubmed citation