As of the latest update, Google Chrome and Microsoft Edge have made a breaking change to how file uploads are handled. Once your system installs this update, you will not be able to upload new images. Please use another browser until we can get it fixed.

Bronchopleural fistula

Bronchopleural fistulas are communications between the bronchial tree and the pleural space.  


They are usually divided as:

  • central: when the fistula involves the trachea or a lobar bronchus
  • peripheral: when a distal airway, either segmental bronchi or the lung parenchyma, communicates to the pleural space
  • postoperative complication of pulmonary resection: considered by far the most common cause, with a reported incidence from 1.5 to 28% after pulmonary resection 1
  • lung necrosis complicating infection or infarction
  • traumatic
    • pneumatoceles 
    • iatrogenic (eg. thoracic tube insertion, lung biopsy, toracocentesis, and nasogastric tube malpositioning)
  • lung neoplasms
    • tumor extension into the pleural space
    • tumor necrosis after chemotherapy or radiotherapy

Radiographic features

Plain radiograph

On chest radiography, the features that may be seen include:

  • steady increase in intrapleural airspace
  • appearance of a new intrapleural gas-pleural fluid collection - i.e. a hydropneumothorax. The gas-fluid level typically extends to the chest wall and shows unequal linear dimensions on orthogonal views conforming to the pleural space
  • changes in an already present gas-fluid level
  • development of tension pneumothorax
  • a drop in the gas-fluid level exceeding 2 cm (if the patient has no chest tube in place)

CT is considered the imaging technique of choice for visualizing and characterizing bronchopleural fistulae 2. CT may show:

Nuclear medicine

Radioaerosol scanning (e.g. xenon ventilation nuclear scintigraphy) has been successfully used in the evaluation of bronchopleural fistulas 5-7. A variety of radioactive tracers may be used, including:

  • technetium-99m (99mTc) albumin colloid fog inhalation
  • 99mTc sulfur colloid
  • 99mTc-labeled diethylenetriamine pentaacetate, krypton, and xenon
  • single photon emission tomography using radiolabeled aerosol inhalation. If there is fistula the radioactive tracer will equilibrate between the postpneumonectomy or pleural space and the airways after inhalation
Share article

Article information

rID: 17012
System: Chest
Synonyms or Alternate Spellings:
  • Bronchopleural fistula
  • Bronchopleural fistulation
  • Broncho-pleural fistula
  • Broncho-pleural fistulation
  • Bronchopleural fistula (BPF)
  • Broncho-pleural fistulas

Support Radiopaedia and see fewer ads

Cases and figures

  • Case 1: plain film
    Drag here to reorder.
  • Case 1: CT
    Drag here to reorder.
  •  Case 2: plain film
    Drag here to reorder.
  • Case 3
    Drag here to reorder.
  • Case 4
    Drag here to reorder.
  • Case 5: following Clagett thoracotomy
    Drag here to reorder.
  • Updating… Please wait.

     Unable to process the form. Check for errors and try again.

     Thank you for updating your details.