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Butterfly glioma

Last revised by Dr Tee Yu Jin on 11 Jan 2021

Butterfly gliomas are a high grade astrocytoma, usually a glioblastoma (WHO grade IV), which crosses the midline via the corpus callosum. Other white matter commissures are also occasionally involved. The term butterfly refers to the symmetric wing-like extensions across the midline. 

Most frequently butterfly gliomas occur in the frontal lobes, crossing via the genu of the corpus callosum, however posterior butterflies are also encountered. 

Treatment and prognosis

Like all high grade gliomas the prognosis is dismal, and usually no attempt at 'curative' resection is made.

Differential diagnosis

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Cases and figures

  • Figure 1: gross pathology
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  • Figure 2: butterfly
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  • Case 1
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  • Case 2: glioblastoma
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  • Case 3
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  • Case 4
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