Cesarean scar ectopic pregnancy
Citation, DOI, disclosures and article data
At the time the article was created Yuranga Weerakkody had no recorded disclosures.
View Yuranga Weerakkody's current disclosuresAt the time the article was last revised Joshua Yap had no financial relationships to ineligible companies to disclose.
View Joshua Yap's current disclosures- Scar ectopic
- Scar ectopic pregnancy
- Cesarean scar ectopic pregnancy (CSEP)
- C section scar ectopic pregnancy
- Cesarean scar ectopic
- C section scar ectopic
- Cesarean scar ectopic pregnancy
- Cesarean scar pregnancy
- Caesarean scar pregnancy
- Cesarean scar pregnancy (CSP)
Cesarean scar ectopic pregnancy is a rare type of abnormal implantation. It is often considered the rarest type of ectopic pregnancy, although some do not include it in this category as implantation occurs within the uterus, instead preferring the term "cesarean scar pregnancy" 6.
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Epidemiology
It has an estimated incidence of ~1:1800-2200 pregnancies 2,3. The overall incidence is however thought to be increasing 4, representing up to 6% of ectopic pregnancies in patients with a history of cesarean section 11.
Pathology
Poor healing can result in a focal thinning of the scar, which may be susceptible to implantation of the gestational sac at this point rather than in the endometrial cavity 10.
Radiographic features
Ultrasound
Described sonographic features include:
- empty uterus
- empty cervical canal
- development of the gestational sac in the anterior part of the lower uterine segment
- an absence of myometrium between the bladder wall and the gestational sac
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Treatment and prognosis
Ultrasound-guided methotrexate injection has emerged as the treatment of choice. Surgical or invasive techniques, including dilatation and curettage, are not recommended due to high morbidity and poor prognosis. Because subsequent pregnancies may also be complicated by uterine rupture, the uterine scar should be evaluated before, as well as during the subsequent pregnancies.
Complications
- uterine rupture
- massive hemorrhage
Differential diagnosis
On ultrasound consider:
- an anterior cervical ectopic pregnancy can have some similar features
- prominent cesarean section scar tissue
- miscarriage in progress
Quiz questions
References
- 1. McKenna D, Poder L, Goldman M, Goldstein R. Role of Sonography in the Recognition, Assessment, and Treatment of Cesarean Scar Ectopic Pregnancies. J Ultrasound Med. 2008;27(5):779-83. doi:10.7863/jum.2008.27.5.779 - Pubmed
- 2. Seow K, Huang L, Lin Y, Lin M, Tsai Y, Hwang J. Cesarean Scar Pregnancy: Issues in Management. Ultrasound Obstet Gynecol. 2004;23(3):247-53. doi:10.1002/uog.974 - Pubmed
- 3. Rotas M, Haberman S, Levgur M. Cesarean Scar Ectopic Pregnancies: Etiology, Diagnosis, and Management. Obstet Gynecol. 2006;107(6):1373-81. doi:10.1097/01.AOG.0000218690.24494.ce - Pubmed
- 4. Levine D. Ectopic Pregnancy. Radiology. 2007;245(2):385-97. doi:10.1148/radiol.2452061031 - Pubmed
- 5. Fylstra D. Ectopic Pregnancy Within a Cesarean Scar: A Review. Obstet Gynecol Surv. 2002;57(8):537-43. doi:10.1097/00006254-200208000-00024 - Pubmed
- 6. Ash A, Smith A, Maxwell D. Caesarean Scar Pregnancy. BJOG. 2007;114(3):253-63. doi:10.1111/j.1471-0528.2006.01237.x - Pubmed
- 7. Seow K, Hwang J, Tsai Y, Huang L, Lin Y, Hsieh B. Subsequent Pregnancy Outcome After Conservative Treatment of a Previous Cesarean Scar Pregnancy. Acta Obstet Gynecol Scand. 2004;83(12):1167-72. doi:10.1111/j.0001-6349.2004.00445.x - Pubmed
- 8. Maymon R, Halperin R, Mendlovic S et al. Ectopic Pregnancies in Caesarean Section Scars: The 8 Year Experience of One Medical Centre. Hum Reprod. 2004;19(2):278-84. doi:10.1093/humrep/deh060 - Pubmed
- 9. Michener C & Dickinson J. Caesarean Scar Ectopic Pregnancy: A Single Centre Case Series. Aust N Z J Obstet Gynaecol. 2009;49(5):451-5. doi:10.1111/j.1479-828X.2009.01067.x - Pubmed
- 10. Chukus A, Tirada N, Restrepo R, Reddy N. Uncommon Implantation Sites of Ectopic Pregnancy: Thinking Beyond the Complex Adnexal Mass. Radiographics. 2015;35(3):946-59. doi:10.1148/rg.2015140202 - Pubmed
- 11. Dibble E & Lourenco A. Imaging Unusual Pregnancy Implantations: Rare Ectopic Pregnancies and More. AJR Am J Roentgenol. 2016;207(6):1380-92. doi:10.2214/AJR.15.15290 - Pubmed
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