Calcifying epithelial odontogenic tumor

Calcifying epithelial odontogenic tumor (CEOT), also known as a Pindborg tumor, (previously has been called adenoid adamintoblastoma, unusual ameloblastoma and cystic odontoma) is typically located in the premolar and molar region of the mandible, although up to a third are found in the maxilla.

Epidemiology

Usually, they are seen in the 4^th to 6^th decades. They are rare tumors.

Pathology

Associations

Half are associated with an unerupted/impacted tooth.

Radiographic features

They are usually radiolucent with scattered areas of calcification, although this can vary from completely radiolucent (seen early on) to more uniformly dense. If present, radiodensities tend to be clustered around a tooth. The cluster of calcific radio-opacities emanating from the central radiodense lesion has been described as a "driven snow" appearance ⁶. 

The margins a variable in appearance, either well defined or indistinct. They can be uni- or multiloculated.

History and etymology

The first case was described in the literature in 1955 by Jens Jørgen Pindborg, Danish oral pathologist (1921-1995) ².

Differential diagnosis

• ameloblastoma: can be difficult to differentiate