Calcinosis circumscripta presents with firm white dermal papules, plaques or subcutaneous nodules which are found in varying distribution. They commonly ulcerate extruding a chalky white material.
It is most often seen in early stages of polymyositis, dermatomyositis, SLE and CREST syndrome but can also be seen following trauma, with connective tissue disorders, insect bites or tumours. Any type of metabolic calcification can also potentially cause calcinosis circumscripta. It is often associated with chronic renal failure.
The pattern of calcinosis circumscripta is usually less extensive than in tumoral calcinosis. The adjacent bone may erode if there is an underyling rheumatic disorder.
- 1. Olsen et.al. Tumoral calcinosis, Pearls, polymics and alterntive diagnoses Radiographics, 26, 871-885, May 2006